产品货号:
Z37334
中文名称:
GCK抗体
英文名称:
Anti-GCK Antibody (Clone#4G6)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GCK Antibody (Clone#4G6) |
指标别名 | GCK;GK;GLK;Glucokinase;glucokinase (hexokinase 4);Hexokinase 4;Hexokinase D;Hexokinase type IV;HHF3;HK IV;HK4;HKIV;HXKP;MODY2 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | GCK |
克隆号 | 4G6 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant fragment of human GCK expressed in E.Coli. |
计算分子量 | 52KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Glucokinase(GCK) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate.Hexokinases phosphorylate glucose to produce glucose-6-phosphate,the first step in most glucose metabolism pathways.Alternative splicing of this gene results in three tissue-specific forms of glucokinase,one found in pancreatic islet beta cells and two found in liver.The protein localizes to the outer membrane of mitochondria.In contrast to other forms of hexokinase,this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant.Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM),maturity onset diabetes of the young,type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). |
Uniprot ID | P35557 |
基因名全称 | Glucokinase |
蛋白名全称 | Glucokinase |
推荐稀释比 | WB 1:500~1:2000 ELISA 1:10000 |
相关搜索:GCK抗体,GCK单抗,Anti-GCK Antibody (Clone#4G6)